Hormone Foundation was developed to target the foundational systems that influence hormone balance, including estrogen metabolism, liver detoxification, gut health, and oxidative stress. The interconnected functions of the liver, gut, and cellular antioxidant defenses play a vital role in how hormones are processed, transformed, and eliminated. Addressing these pathways is essential not only for managing hormonal shifts, but also for supporting the body’s resilience and long-term hormonal equilibrium.

This comprehensive, systems-based approach is what makes Hormone Foundation unique: It supports the body’s natural ability to process hormones efficiently, neutralize reactive metabolites, and maintain healthy estrogen balance through targeted detoxification and defense mechanisms—without overwhelming or overstimulating a single pathway. It does this by utilizing key bio actives including the Complete Turmeric Matrix, hops strobile extract, black kale extract, Quatrefolic^® folate, epigallocatechin gallate (EGCg), and tributyrin (CoreBiome^®).

Tributyrin

Tributyrin is a short-chain fatty acid that enhances gut-derived estrogen detoxification by nourishing beneficial bacteria involved in the elimination of estrogen metabolites.

Black kale seed extract

Black kale seed extract is a precursor to sulforaphane, a potent compound that supports Phase II liver detoxification.

EGCG from Green Tea Leaf Extract

EGCG from Green Tea Leaf Extract provides antioxidant support and helps balance estrogen metabolism

Complete Turmeric Matrix

Complete Turmeric Matrix delivers curcuminoids supporting a balanced inflammatory response.

Quatrefolic

Quatrefolic is a bioavailable form of folate which plays an important role in supporting methylation in phase II of estrogen detoxification.

Hops

Hops support estrogen metabolism via receptor modulation and phytoestrogenic activity, and by directly supporting Phase I of estrogen detoxification.